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Pro-Xylane

Plamed Vision: Become the leader of natural cosmetic ingredients for sensitive skin.

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Pro-Xylane

Pro-Xylane

  • No irritating odor, no toxicity, low content of acetic acid and borate, won’t affect the formulation.
  • Good water solubility and stability, not easy oxidation, easily absorbed by skin.
Plamed is the largest Pro-Xylane supplier in China with good Pro-Xylane price and high quality. Where to buy Pro-Xylane with reasonable price and high quality? Where to find good information of wholesale Pro-Xylane? As the professional Pro-Xylane manufacturer, Plamed is your best choice.

Pro-Xylane, also known as hydroxypropyl tetrahydropyrantriol, is a glycoprotein mixture derived from xylose. Since xylose exists in large quantities in beech trees, it has the ability to promote the production of glucosaminoglycans, namely mucopolysaccharides (GAGs). Also, xylose can provide binding sites for GAGs, start the generation and assembly of GAGs in the skin, and improve the deficiency of GAGs caused by skin aging. Studies have shown that Pro-Xylane is easy to biodegrade, does not accumulate in organisms, and has no toxicity.

Plamed develops 2 kinds of Pro-Xylane, 30% liquid and 98% powder. Both are water-soluble It can be used in skincare products for anti-aging.

 

Pro-xylane

Product Name CAS Number INCI Name
Pro-Xylane 439685-79-7 HYDROXYPROPYL TETRAHYDROPYRANTRIOL
Molecular Weight Molecular Formula Molecular Structure
192.21g/mol C8H16O5
Product ID Specification Minimal Package Minimal Order Quantity
PMKZ2201 30% liquid 1kg 1kg
PMKZ2202 98% powder 1kg 1kg

The inventor of Pro-Xylane, Dr. Maria DALKO-CSIBA, a scientist at the L’Oreal R&D and Innovation Center, is based on this characteristic of xylose, using a large number of beech and birch trees that exist in nature. In 1999-2000, he led the team to synthesize more than 200 kinds of xylose derivatives. Based on comprehensive consideration of factors such as efficacy, safety, stability and skin bioavailability, Pro-Xylane was finally successfully screened out. Nowadays, Pro-Xylane mainly obtained by chemical synthesis.

98% Powder Specification

Items Specification
Purity ≥99% HPLC
Appearance White to off-white powder
Odor Characteristic
Physical Characteristics
Loss on drying ≤3.0%
pH (10% water solution) 4.0-8.0
Heavy Metals
Pb ≤10ppm
As ≤2ppm
Hg ≤1ppm
Cd ≤5ppm
Microbiological Tests
Total plate count ≤1000cfu/g
Yeast & mold ≤100cfu/g
Pseudomonas aeruginosa Negative
Staphylococcus aureus Negative
Heat-resistant escherichia coli Negative
  • Anti-aging

Studies have proved that Pro-Xylane can exert biological effects at different layers of the skin

  • Acting on the epidermis, Pro-Xylanecan promote the synthesis of various GAGs, and at the same time up-regulate the expression of hyaluronic acid receptor CD44 and syndecan, thereby activating the signal pathway mediated by GAGs. Clinical studies have shown that topical application of Pro-Xylane can effectively reduce transepidermal water loss, improve skin barrier function, and promote epidermal renewal, making the skin plump and radiant.

  • At the Dermal-Epidermal Junction (DEJ), Pro-Xylanecan up-regulate collagen type IV (the main component of the lamina densa), laminin, type VII collagen (the main component of anchoring fibrils) and other key proteins. Then it can induce the expression of proteoglycanperlecan, and strengthen the tightness and stability of DEJ structure. Clinical studies have shown that in aging skin samples, the ultra-microscopic structure of DEJ presents the aging characteristics in several areas. After local application of Pro-Xylane, the DEJ structure of aging skin can be made more uniform and clear, the re-duplication of lamina densa is significantly reduced, making the skin structure stronger.

  • In the dermis, Pro-Xylanecan promote the production of various GAGs such as hyaluronic acid and heparan sulfate. In addition, the up-regulation of the expression of type I procollagen and fibrillin-1 is observed, suggesting that the production of GAGs and collagen. They are both important dermal extracellular matrix components that maintain skin elasticity and firmness. Therefore, it has been proved in clinical research that topical application of Pro-Xylane can effectively improve the fine lines and wrinkles of the skin, and make the skin firm and elastic.
  • Skin Repair

In vitro skin experiments, Pro-Xylane is able to reconstruct the complete structure of the epidermodermal layer, and it also had similar function as retinoic acid, enhancing the thickness of the stratum corneum and providing barrier function, but without irritation.

Pro-Xylane is mainly used in anti-aging, skin repair, anti-wrinkle skincare products, such as serum, facial mask, emulsion, toner, essence, cream, etc.

Product Reference Dosage
30% Pro-Xylane 0.2%-3% in leave-on cosmetics
0.3-5% in wash-off cosmetics
98% Pro-Xylane 0.5%-2%

Pro-Xylane application cases in major cosmetic brands in the world:

Brand Product
L’Oreal RevitaLift Triple Power Eye Treatment 

Revitalift Triple Power Intensive Anti-Aging Moisturizer
SkinCeuticals  Hyaluronic Acid Intensifier Hydrating Serum 

A.G.E. Interrupter Moisturizer
Biotherm Homme Force Supreme Lotion
La Roche-Posay Substiane Serum 

Substiane [+] UV SPF 15

Hyalu B5 Hyaluronic Acid Eye Cream
Estee Lauder  RE-NUTRIV Ultimate Lift Regenerating Youth Serum
LANCOME Absolue demaquillant gel 

ABSOLUE L’EXTRAIT ULTIMATE EYE CONTOUR COLLECTION

ABSOLUE REVITALIZING EYE SERUM

Absolue White Aura
KIEHL’S Hydrating & Clarifying Treatment Masque 

KIEHL’S Clearly corrective dark spot solution
Vichy Neovadiol Compensating Complex Night Cream 

Neovadiol complexe substitutif day cream

IDEALIA DAY CARE
  • CTFAhas recognized HYDROXYPROPYL TETRAHYDROPYRANTRIOL as a raw material for cosmetics;
  • The International Catalogue of Chinese Cosmetic Raw Materials Standardsin 2018 issued by HYDROXYPROPYL TETRAHYDROPYRANTRIOL.
  • On the Announcement of Name List of Cosmetics Raw Materialpublished by CFDA in 2021 both include HYDROXYPROPYL TETRAHYDROPYRANTRIOL.

Package: 1kg/bag, 1kg/bottle

Storage: Store in cool and dry place at room temperature, keep away from strong light.

  1. Pro-Xylane Benefits for Anti-Aging

  2. Top 5 Best Anti-aging Ingredients for Skincare

  3.  Pro-xylane Anti-aging Uses for Skincare

Plamed focuses on natural cosmetic ingredients for more than 10 years. We have founded four subsidiary companies, which respectively develops different kinds of cosmetic raw material. Plamed is a company whose CEO is designated as the first secretary general of Shaanxi Plant Extraction Association.

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